Selected Publications and Presentations

 


 

 

 

2024

 

 

Dhirachaikulpanich D, Xie J, Chen X, Li X, Madhusudhan S, Zheng Y, Beare NAV. Using Deep Learning to Segment Retinal Vascular Leakage and Occlusion in Retinal Vasculitis. Ocul Immunol Inflamm. 2024 Jan 23:1-8. doi: 10.1080/09273948.2024.2305185. Epub ahead of print. PMID: 38261457.

 

Woof W, de Guimarães TAC, Al-Khuzaei S, Varela MD, Sen S, Bagga P, Mendes B, Shah M, Burke P, Parry D, Lin S, Naik G, Ghoshal B, Liefers B, Fu DJ, Georgiou M, Nguyen Q, da Silva AS, Liu Y, Fujinami-Yokokawa Y, Kabiri N, Sumodhee D, Patel P, Furman J, Moghul I, Sallum J, De Silva SR, Lorenz B, Holz F, Fujinami K, Webster AR, Mahroo O, Downes SM, Madhusudhan S, Balaskas K, Michaelides M, Pontikos N. Quantification of Fundus Autofluorescence Features in a Molecularly Characterized Cohort of More Than 3000 Inherited Retinal Disease Patients from the United Kingdom. medRxiv [Preprint]. 2024 Mar 28:2024.03.24.24304809. doi: 10.1101/2024.03.24.24304809. PMID: 38585957; PMCID: PMC10996753.

 

Dhirachaikulpanich D, Xie J, Chen X, Li X, Madhusudhan S, Zheng Y, Beare NAV. Using Deep Learning to Segment Retinal Vascular Leakage and Occlusion in Retinal Vasculitis. Ocul Immunol Inflamm. 2024 Jan 23:1-8. doi: 10.1080/09273948.2024.2305185. Epub ahead of print. PMID: 38261457.

 

Gale RP, Airody A, Sivaprasad S, Hanson RLW, Allgar V, McKibbin M, Morland AB, Peto T, Porteous M, Chakravarthy U; FASBAT Study Group. Improved structure and function in early detected second eye neovascular age-related macular degeneration; FASBAT/EDNA report 1. Ophthalmol Retina. 2024 Jan 1:S2468-6530(23)00674-7. doi: 10.1016/j.oret.2023.12.012. Epub ahead of print. PMID: 38171416.

2023

 

 

Dhirachaikulpanich, Dhanach MD*,†,‡; Madhusudhan, Savita FRCOphth*,‡; Parry, David FdA‡; Babiker, Salma FRCOphth‡; Zheng, Yalin PhD*,‡,§; Beare, Nicholas A.V. FRCOphth, MD*,‡. RETINAL VASCULITIS SEVERITY ASSESSMENT: Intraobserver and Interobserver Reliability of a New Scheme for Grading Wide-Field Fluorescein Angiograms in Retinal Vasculitis. Retina 43(9):p 1534-1543, September 2023. | DOI: 10.1097/IAE.0000000000003838

 

Zhou Y, Chia MA, Wagner SK, Ayhan MS, Williamson DJ, Struyven RR, Liu T, Xu M, Lozano MG, Woodward-Court P, Kihara Y; UK Biobank Eye & Vision Consortium; Altmann A, Lee AY, Topol EJ, Denniston AK, Alexander DC, Keane PA. A foundation model for generalizable disease detection from retinal images. Nature. 2023 Oct;622(7981):156-163. doi: 10.1038/s41586-023-06555-x. Epub 2023 Sep 13. PMID: 37704728; PMCID: PMC10550819.

Warwick AN, Curran K, Hamill B, Stuart K, Khawaja AP, Foster PJ, Lotery AJ, Quinn M, Madhusudhan S, Balaskas K, Peto T; UKBB Eye and Vision Consortium. UK Biobank retinal imaging grading: methodology, baseline characteristics and findings for common ocular diseases. Eye (Lond). 2023 Jul;37(10):2109-2116. doi: 10.1038/s41433-022-02298-7. Epub 2022 Nov 3. Erratum in: Eye (Lond). 2023 Jan 5;: PMID: 36329166; PMCID: PMC10333328.

 

Kastner A, Stuart KV, Montesano G, De Moraes CG, Kang JH, Wiggs JL, Pasquale LR, Hysi P, Chua SYL, Patel PJ, Foster PJ, Khaw PT, Khawaja AP; UK Biobank Eye and Vision Consortium. Calcium Channel Blocker Use and Associated Glaucoma and Related Traits Among UK Biobank Participants. JAMA Ophthalmol. 2023 Oct 1;141(10):956-964. doi: 10.1001/jamaophthalmol.2023.3877. PMID: 37676684; PMCID: PMC10485742.

 

Foster PJ, Atan D, Khawaja A, Lotery A, MacGillivray T, Owen CG, Patel PJ, Petzold A, Rudnicka A, Sun Z, Sheard S, Allen N; UK Biobank and UK Biobank Eye and Vision Consortium. Cohort profile: rationale and methods of UK Biobank repeat imaging study eye measures to study dementia. BMJ Open. 2023 Jun 23;13(6):e069258. doi: 10.1136/bmjopen-2022-069258. PMID: 37355273; PMCID: PMC10314584.

 

Dhirachaikulpanich D, Madhusudhan S, Parry D, Babiker S, Zheng Y, Beare NAV. RETINAL VASCULITIS SEVERITY ASSESSMENT: Intraobserver and Interobserver Reliability of a New Scheme for Grading Wide-Field Fluorescein Angiograms in Retinal Vasculitis. Retina. 2023 Sep 1;43(9):1534-1543. doi: 10.1097/IAE.0000000000003838. PMID: 37229721; PMCID: PMC10442128.

 

Meng Y, Zhang H, Zhao Y, Gao D, Hamill B, Patri G, Peto T, Madhusudhan S, Zheng Y. Dual Consistency Enabled Weakly and Semi-Supervised Optic Disc and Cup Segmentation With Dual Adaptive Graph Convolutional Networks. IEEE Trans Med Imaging. 2023 Feb;42(2):416-429. doi: 10.1109/TMI.2022.3203318. Epub 2023 Feb 2. PMID: 36044486.

2022

 

 

Nguyen Q, Woof W, Kabiri N, Sen S, Daich Varela M, Cabral De Guimaraes TA, Shah M, Sumodhee D, Moghul I, Al-Khuzaei S, Liu Y, Hollyhead C, Tailor B, Lobo L, Veal C, Archer S, Furman J, Arno G, Gomes M, Fujinami K, Madhusudhan S, Mahroo OA, Webster AR, Balaskas K, Downes SM, Michaelides M, Pontikos N; Eye2Gene Patient Advisory Group. Can artificial intelligence accelerate the diagnosis of inherited retinal diseases? Protocol for a data-only retrospective cohort study (Eye2Gene). BMJ Open. 2023 Mar 20;13(3):e071043. doi: 10.1136/bmjopen-2022-071043. PMID: 36940949; PMCID: PMC10030964.

 

Barbra Hamill, Tunde Peto, Dongxu Gao, Godhuli Patri, Savita Madhusudhan, Yalin Zheng, Paul Foster, Konstantinos Balaskas, Michael Joseph Quinn, Pauline Lenfestey, David Parry, Sophie Leach, Muldrew Alyson, Laura Cushley, Alan Sproule, catherine Jamison; Optic disc features in UKBIOBANK (UKBB) and the novel deep learning (DL) algorithm for automated prediction of cup-disc ratio (CDR) from colour fundus (CF) images.. Invest. Ophthalmol. Vis. Sci. 2022;63(7):1647 – A0142

 

Alasdair Warwick, Barbra Hamill, Katie Curran, Anthony Khawaja, Andrew J Lotery, Paul Foster, Konstantinos Balaskas, Michael Joseph Quinn, Savita Madhusudhan, Alan Sproule, Sophie Leach, Daniela Florea, Muldrew Alyson, Laura Cushley, Graham Young, Tunde Peto; Characterising individuals with retinopathy from retinal image grading data in UK Biobank. Invest. Ophthalmol. Vis. Sci. 2022;63(7):814.

2021

 

 

Lotery A, Sivaprasad S, O’Connell A, Harris RA, Culliford L, Cree A, Madhusudhan S, Griffiths H, Ellis L, Chakravarthy U, Peto T, Rogers CA, Reeves BC. Eplerenone versus placebo for chronic central serous chorioretinopathy: the VICI RCT. Southampton (UK): NIHR Journals Library; 2021 Jan. PMID: 33471454.

 

Maunz A, Benmansour F, Li Y, Albrecht T, Zhang YP, Arcadu F, Zheng Y, Madhusudhan S, Sahni J. Accuracy of a Machine-Learning Algorithm for Detecting and Classifying Choroidal Neovascularization on Spectral-Domain Optical Coherence Tomography. J Pers Med. 2021 Jun 8;11(6):524. doi: 10.3390/jpm11060524. PMID: 34201045; PMCID: PMC8227725.

 

Halim S, Nugawela M, Chakravarthy U, Peto T, Madhusudhan S, Lenfestey P, Hamill B, Zheng Y, Parry D, Nicholson L, Greenwood J, Sivaprasad S. Topographical Response of Retinal Neovascularization to Aflibercept or Panretinal Photocoagulation in Proliferative Diabetic Retinopathy: Post Hoc Analysis of the CLARITY Randomized Clinical Trial. JAMA Ophthalmol. 2021 May 1;139(5):501-507. doi: 10.1001/jamaophthalmol.2021.0108. PMID: 33704351; PMCID: PMC7953330.

2020

 

 

Lotery A, Sivaprasad S, O'Connell A, Harris RA, Culliford L, Ellis L, Cree A, Madhusudhan S, Behar-Cohen F, Chakravarthy U, Peto T, Rogers CA, Reeves BC; VICI trial investigators. Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI): a randomised, double-blind, placebo-controlled trial. Lancet. 2020 Jan 25;395(10220):294-303. doi: 10.1016/S0140-6736(19)32981-2. PMID: 31982075.

 

Wu X, Gao D, Borroni D, Madhusudhan S, Jin Z, Zheng Y. Cooperative Low-Rank Models for Removing Stripe Noise From OCTA Images. IEEE J Biomed Health Inform. 2020 Dec;24(12):3480-3490. doi: 10.1109/JBHI.2020.2997381. Epub 2020 Dec 4. PMID: 32750910.

2019

 

 

Usha Chakravarthy, Tunde Peto, Rebecca Evans, Simon P Harding, Barney Reeves; Retinal morphology and risk factors for the development of macular atrophy during extended follow up in the IVAN trial. Invest. Ophthalmol. Vis. Sci. 2019;60(9):4223.

2018

 

 

Agorogiannis, E.I., Pearce, I.A., Yadav, S. et al. Clinical outcomes in Caucasian patients with polypoidal choroidal vasculopathy. Eye 32, 1731–1739 (2018). https://doi.org/10.1038/s41433-018-0168-2

 

2017

 

 

Halim S, Nugawela M, Chakravarthy U, Peto T, Madhusudhan S, Lenfestey P, Hamill B, Zheng Y, Parry D, Nicholson L, Greenwood J, Sivaprasad S. Topographical Response of Retinal Neovascularization to Aflibercept or Panretinal Photocoagulation in Proliferative Diabetic Retinopathy: Post Hoc Analysis of the CLARITY Randomized Clinical Trial. JAMA Ophthalmol. 2021 May 1;139(5):501-507. doi: 10.1001/jamaophthalmol.2021.0108. PMID: 33704351; PMCID: PMC7953330.

2015

 

 

Chakravarthy U, Harding SP, Rogers CA, Downes S, Lotery AJ, Dakin HA, Culliford L, Scott LJ, Nash RL, Taylor J, Muldrew A, Sahni J, Wordsworth S, Raftery J, Peto T, Reeves BC. A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN). Health Technol Assess. 2015 Oct;19(78):1-298. doi: 10.3310/hta19780. PMID: 26445075; PMCID: PMC4781416.

 

MacCormick IJ, Maude RJ, Beare NA, Borooah S, Glover S, Parry D, Leach S, Molyneux ME, Dhillon B, Lewallen S, Harding SP. Grading fluorescein angiograms in malarial retinopathy. Malar J. 2015 Sep 24;14:367. doi: 10.1186/s12936-015-0897-7. PMID: 26403288; PMCID: PMC4583163.

 

Zhao Y, MacCormick IJ, Parry DG, Beare NA, Harding SP, Zheng Y. Automated Detection of Vessel Abnormalities on Fluorescein Angiogram in Malarial Retinopathy. Sci Rep. 2015 Jun 8;5:11154. doi: 10.1038/srep11154. PMID: 26053690; PMCID: PMC4459173.

 

Zhao Y, MacCormick IJ, Parry DG, Leach S, Beare NA, Harding SP, Zheng Y. Automated detection of leakage in fluorescein angiography images with application to malarial retinopathy. Sci Rep. 2015 Jun 1;5:10425. doi: 10.1038/srep10425. PMID: 26030010; PMCID: PMC4450752.

2013

 

 

Simon Harding, Barnaby Reeves, Alyson Muldrew, David Parry, Chris Rogers, Jayashree Sahni, Tunde Peto, Usha Chakravarthy, IVAN Study Group; The Relationship between Haemorrhage and OCT Signs and the Likelihood of Neovascular AMD being Active during Follow-up: Data from the IVAN study. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3660.

2012

 

 

Yalin Zheng, David Parry, George Morphis, Simon Harding; Motion-free Stereo Fluorescein Angiogram (FA) Sequence. Invest. Ophthalmol. Vis. Sci. 2012;53(14):4103.

2010

 

 

Y. Zheng, C. Campa, A. N. Stangos, D. Parry, J. Deane, S. P. Harding; Fast Automated Segmentation of Fluid Spaces in Fourier-Domain OCT Images of the Retina. Invest. Ophthalmol. Vis. Sci. 2010;51(13):1784.

2008

 

 

D.J.J. Farnell, F.N. Hatfield, P. Knox, M. Reakes, S. Spencer, D. Parry, S.P. Harding,

Enhancement of blood vessels in digital fundus photographs via the application of multiscale line operators, Journal of the Franklin Institute, Volume 345, Issue 7,2008, 0032, https://www.sciencedirect.com/science/article/abs/pii/S001600320800046X?via%3Dihub

 

W. P. Patton, K. A. Muldrew, T. Peto, S. P. Harding, P. Lenfesty, U. Chakravarthy; Lesion Components in Eyes of Patients With Neovascular AMD Without Active CNV: Analysis of a Subset of Angiograms Graded in the VPDT Cohort Study for the UK. Invest. Ophthalmol. Vis. Sci. 2008;49(13):578.

 

T. Peto, W. P. Patton, A. K. Muldrew, P. Lenfestey, B. Reeves, S. P. Harding, U. Chakravarthy, VPDT Cohort Study Team; Concordance of Fluorescein Angiography Grading at the Network of Ophthalmic Reading Centres in the United Kingdom. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2248.

2007

 

 

K. A. Muldrew, W. P. Patton, T. Peto, M. R. Stevenson, B. Reeves, U. Chakravarthy, P. Lenfestey, S. P. Harding, VPDT Cohort Study Team; One Year Results of Quality Assurance in the UK VPDT Cohort Study Reading Centre Network. Invest. Ophthalmol. Vis. Sci. 2007;48(13):5105.